منابع مشابه
Melanoma resistance to photodynamic therapy: new insights.
Melanoma is the most dangerous form of skin cancer, with a steeply rising incidence and a poor prognosis in its advanced stages. Melanoma is highly resistant to traditional chemotherapy and radiotherapy, although modern targeted therapies such as BRAF inhibitors are showing some promise. Photodynamic therapy (PDT, the combination of photosensitizing dyes and visible light) has been tested in th...
متن کاملResistance to Targeted Therapies in Melanoma: New Insights
Several molecular mechanisms are involved in melanoma genesis and progression. Molecular targets for effective therapeutic intervention have been identified within the RAS-RAF-MEK-ERK and, to a less extent, PI3K-AKT pathways. The development of inhibitors of key effectors (mainly BRAF mutant, MEK, and KIT) into such pathways has significantly improved the treatment of patients with advanced mel...
متن کاملNew insights in pathophysiology of contact hypersensitivity: From transgenic mice to human pathology
.
متن کاملHIV–1 resistance to dolutegravir: update and new insights
Integrase strand transfer inhibitors (INSTIs) are the latest class of potent anti-HIV drugs. Currently, three INSTIs have been approved by the US Food and Drug Administration: raltegravir (RAL), elvitegravir (EVG) and dolutegravir (DTG). Resistance mutations to RAL and EVG emerge rapidly, and significant cross-resistance between these compounds has been documented. In addition, limited cross-re...
متن کامل- Insights in to infertility and modern therapies -
In general, infertility is defined as the inability of couples to conceive after one year of unprotected sex. Causes of infertility can be related to both men and women. Unexplained infertility refers to the absence of a definable cause for a couplechr(chr('39')39chr('39'))s failure to achieve pregnancy, even after standard diagnostic methods including semen analysis, endometrial biopsy, etc. H...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Transportation Research Procedia
سال: 2015
ISSN: 2352-1465
DOI: 10.1016/j.trpro.2015.06.043